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Muscular Dystrophy

There is a group of muscle diseases and disorders, which are called muscular dystrophy that are genetically transmitted.

Perhaps one of the best known muscle dystrophies is the Duchenne dystrophy, which is X-linked and recessive. It is typical for this muscle dystrophy to lead to progressive weakness in the upper arm and thigh muscles. The muscle fibers are destroyed and replaced with connective tissue.

It occurs mostly in males and affects 1 in 3000 live male births.


The weakness begins to show in boys starting at the age of 3 to 7 years. It progresses relentlessly with symptoms of muscle weakness and frequent falls. The pelvic muscles are affected first, but later the shoulder muscles also are affected. Difficulties are encountered walking upstairs and getting up from a sitting position.

Diagnostic Tests

Muscle biopsies for special histological studies are usually the decisive tests confirming the clinical diagnosis.

 Muscular Dystrophy

Muscular Dystrophy


Unfortunately there is no treatment that is effective. The prognosis is poor with most patients getting wheelchair bound by the time they are 10 to 12. The breathing muscles are eventually affected as is the heart muscle leading to premature death by the age of 18 to 20 for most patients. Patients die of lung infections, aspiration pneumonia,respiratory failure, heart arrhythmias and heart failure.

A less severe variant of muscle dystrophy is the Becker muscular dystrophy where patients may survive until the age of 35 to 40.



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Last modified: November 10, 2014

This outline is only a teaching aid to patients and should stimulate you to ask the right questions when seeing your doctor. However, the responsibility of treatment stays in the hands of your doctor and you.