As indicated under “lymphomas” there are several disease entities contained in non-Hodgkin’s disease (also called non-Hodgkin’s lymphoma, NHL), which is common and multifaceted. NHL can be brought on by different causes. For instance, human T-cell leukemia-lymphoma virus(HTLV-1) is endemic in southern Japan, South America, the Caribbean and the southeastern USA and is the cause of an acute illness called the adult T-cell leukemia-lymphoma. This is one of the NHLs and it presents with an aggressive type illness with skin involvement, generalized lymph gland swelling, enlargement of spleen and liver and a leukemia, where the leukemia cells are malignant T lymphocytes.
With most NHL cases the B cells (the antibody producing cells attacking viruses and bacteria) of the immune system are affected with a malignant transformation. In the minority of cases the other branch of the immune system, T cells (killer T cells that get rid of parasites and cancer cells). Common subtypes of NHL are diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma, both of which occur in people in their mid 60’s.
Here is an overview of many more less common forms of non-Hodgkin’s lymphoma (NHL).
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