Transient Ischemic Attacks (TIA)

A neurological deficit similar to a mini stroke, but very fleeting in nature and completely reversible within a 1 or 2 hour period, is called a transient ischemic attack. Depending on he underlying pathology this might be harmless or it might be the first sign of an impending disaster. It warrants a careful work-up by a neurologist.

Symptoms:

There is a sudden presentation a focal neurological symptom such as loss of speech, numbness and lack of power in one extremity or visual problems. However, the symptoms only last a few minutes up to at the most 1 or 2 hours. There is no loss of consciousness. These attacks could happen as isolated events, but often happen intermittently 2 or 3 times in a year. If there are frequent TIA's, the patient is at a significantly higher risk of developing a full stroke.

Diagnosis:

Because of the possibility of an impending stroke the presence of an ischemic attack should be considered like a possible first warning of an impending stroke.

In other words, nature gave us a grace period to sort out what is going on. Tests should include a CT scan of the brain and possibly angiogram of the blood vessels to the brain, particularly images of the carotid and vertebral arteries. Ultrasound Doppler studies would also be useful to examine the bifurcation of the carotid arteries and the blood flow through the major neck vessels. An echocardiogram to look for abnormalities of the heart valves would be another useful test. The rationale of all these tests is that the physician is looking for causes for shedding of emboli such as from ragged heart valves or arteriosclerotic plaques in the carotid arteries or the vertebral arteries. The CT scan of the brain rules out an existing stroke, scarring from a previous stroke, a brain tumor and an aneurysm. Some blood tests are also done to rule out diabetes mellitus and autoimmune diseases such as lupus erythematosus.

Treatment:

Sometimes, if the physician finds a marked arteriosclerotic change in the carotid artery with a narrowing of the lumen of 70% or more, a cardiovascular procedure called endarterectomy has proven to be very valuable, as it will not only stop the TIA , but also prevent a stroke.

However, not all findings are as clear as that and the recommendation by the physician will depend on the findings of these and other tests. In the case of a minimal narrowing or the vertebral arteries or carotid arteries, the doctor may prescribe ASA or ticlopidine (brand name: Ticlid, Apo-Ticlopidine or Nu-Ticlopidine) as antiplatelet drugs. With atrial fibrillation as a heart rhythm and blood clots that are shed from the heart chambers, anticoagulant therapy with heparin initially, then a switch-over to Coumadin would be the therapy of choice. In the case of a singular metastasis in the brain from a previously treated melanoma, for instance, life can often be prolonged by an excision of the brain metastasis by a neurosurgeon. This may or may not be followed by radiation therapy.

Pain relief:

There is an FDA approved non-drug method available, IceWave patches from Lifewave, which will control pain and headaches. This is mentioned in the book "Breakthrough" by Suzanne Somers (Ref. 12) where newer insights of antiaging medicine are also reviewed. Although the patches are placed over acupuncture points, there are no needles involved. Nanotechnology, a newer technology, was used in the manufacturing of these patches and infrared (heat) waves from body heat are utilized to stimulate an acupuncture point, which modifies pain perception and reduces pain to half or less. Medically this would be considered an excellent pain reliever. For more info on the patches see the IceWave patches from Lifewave link above (click "products"). In the US a 5 pack of the IceWave spray is available that can be directly sprayed onto the skin in the area where the pain is located.

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Disclaimer:

This outline is only a teaching aid to patients and should stimulate you to ask the right questions when seeing your doctor. However, the responsibility of treatment stays in the hands of your doctor and you.

References:

1. KH Lee et al. Arch Neurol 2000 Jul 57(7): 1000-1008.

2. S Schmulling et al. Stroke 2000 Jul 31(7): 1552-1554.

3. D Jackson et al. Clin Rehabil 2000 Oct 14(5): 538-547.

4. ML Hackett et al. Neurology 2000 Sep 12; 55 (5): 658-662.

5. K Tsutsumi et al. J Neurosurg 2000 Oct 93( 4): 550-553.

6. IS Spetzler Surg Neurol 2000 Jun 53(6): 530-540.

7. G Lot et al. Acta Neurochir (Wien) 1999; 141(6): 557-562.

8. The Merck Manual, 7th edition, by M. H. Beers et al., Whitehouse Station, N.J., 1999. Chapter 174.

9. Noble: Textbook of Primary Care Medicine, 3rd ed.,2001, Mosby Inc.

10. Ferri: Ferri's Clinical Advisor: Instant Diagnosis and Treatment, 2004 ed., Copyright © 2004 Mosby, Inc.

11. Rakel: Conn's Current Therapy 2004, 56th ed., Copyright © 2004 Elsevier

12. Suzanne Somers: "Breakthrough" Eight Steps to Wellness-- Life-altering Secrets from Today's Cutting-edge Doctors", Crown Publishers, 2008

Last Modified: July 1, 2009